SMRL: Stanford NMR Facility and Resource

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INTERNATIONAL SCHOOL OF STRUCTURAL
BIOLOGY AND MAGNETIC RESONANCE

6th Course:
STRUCTURE, DYNAMICS AND FUNCTION
OF BIOLOGICAL MACROMOLECULES AND ASSEMBLIES

EMFCSC logo ERICE-SICILY: 10-22 July 2003
Ettore Majorana Foundation
and Centre for Scientific Culture

A NATO Advanced Study Institute

DIRECTORS OF THE COURSE:
Jody Puglisi: Puglisi@Stanford.Edu
Puglisi Group, SMRL, Structural Biology, Stanford University
(All correspondences should be directed to Prof. Puglisi)

Narcyz Pislewski: Narcyz.Pislewski@ifmpa n.poznan.pl
Institute of Molecular Physics, Polish Academy of Sciences

REGISTRAR:
Manolia Margaris: Manolia@Stanford.Edu
SMRL, Puglisi Group, Stanford University

DIRECTOR OF THE SCHOOL:
Oleg Jardetzky: Molecular Pharmacology, Stanford University

DIRECTOR OF THE CENTRE:
Antonino Zichichi

SPONSORED BY:
The Italian Ministry of Education
The Italian Ministry of University and Scientific-Technological Research
The Sicilian Regional Government


PURPOSE OF THE COURSE:

The school will teach the principles of biomolecular structure determination by crystallography and NMR, and how dynamics measurements are made and computed on biological systems. The integration of other biophysical methods for the study of dynamics will also be stressed.

Modern Techniques for the study of structure, dynamics and function of biological macromolecules and assemblies:

NMR Spectroscopy
X-ray Crystallography
Molecular Dynamics
Macromolecular Function and Design
Single-molecule fluorescence

Specific topics:

Principles of NMR
Optical Spectroscopy
Principles of X-ray Crystallography
Nucleic acids and protein complexes
NMR Physics
Novel methods for structure determination of proteins and complexes
Protein-nucleic acid complexes
Single-molecule methods
Drug design
Large RNA NMR
Molecular dynamics simulations
Protein design and folding
Molecular recognition


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© 2002 Stanford University, All Rights Reserved.
Manolia@Stanford.Edu