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NATO Advanced Study Institute

This course will provide an overview of physical and structural methods in biology and will present technologies related to pathogen detection and treatment using these methods. Both, basic principles and concrete examples will be presented in a long course format.

Topics Include:

Principles of NMR spectroscopy
Principles of X-ray diffraction
Single-molecule methods
Cryoelectron microscopy
Molecular dynamics and other computational approaches
Structure refinement
Mass spectrometry
Use of NMR data to calculate protein and nucleic acid structures
New RNA and protein NMR methods
Fluorescence spectroscopy and modeling
Nucleic acid structure
In Vivo methods
Viral pathogens
Bacterial pathogens
Antivirals
Ribosome structure
Translational mechanism and antibiotics
New technologies to study proteins
Solid state NMR
Peptides as drugs
Membrane proteins as drug targets
Structure-based drug design in biotechnology
NMR and physical studies of pathogenic proteins
Coupling genomics and structural studies

Tutorials:

Pathogenesis of bioterror agents
Computational biology and experiment
Technology and the environment
Spectroscopic approaches
Roundtable and tutorial on genome-wide approaches and biophysics
Student-lecturer discussion on future perspectives
Student presentations including a poster session

• Alexander ARSENIEV, Russian Academy of Sciences, RU
  
• Axel BRUNGER, Stanford University, US
  
• Muriel DELEPIERRE, Institute Pasteur, FR
  
• Roman EFREMOV, Russian Academy of Sciences, RU
  
• Mans EHRENBERG, University of Uppsala, SE
  
• Angela GRONENBORN, University of Pittsburgh, US
  
• David LILLEY, University of Dundee, UK
  
• Alexander McPHERSON, University of California, Irvine, US
  
• Hartmut OSCHKINAT, Berlin Institute of Molecular Pharmacology, GE
  
• Jody PUGLISI, Stanford University, US
  
• Gian Luigi ROSSI, University of Parma, IT
  
• Phillip SELENKO, Leibniz-Institut fŸr Molekulare Pharmakologie, DE
  
• Alexander SHIVANYUK, National University of Kiev, UA
  
• Brian SYKES, University of Alberta, CA
  
• Ada YONATH, Weizmann Institute, IL
  

Fee: 1,100 Euro.

Fee includes:

(a) lodging accommodations for the duration of the course at the Ettore Majorana Centre;
(b) all meals (breakfast, lunch, dinner) for the duration of the school;
(c) Banquet Evening;
(d) one excursion day; and,
(e) transportation from the point of entry (Palermo airport or railroad station) as well as return transportation to the same.

Applications Closed. Look for us at the next Erice conference.

For additional information please contact:

Ms. Manolia Margaris
E-mail: manolia @at@ stanford.edu (replace " @at@ " with "@")