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This course will provide an overview of physical and structural methods in biology and will present technologies related to pathogen detection and treatment using these methods. Both, basic principles and concrete examples will be presented in a long course format.

Topics Include:

Principles of NMR spectroscopy
Principles of X-ray diffraction
Single-molecule methods
Cryoelectron Microscopy
Molecular dynamics and other computational approaches
Mass spectrometry
Use of NMR data to calculate protein and nucleic acid structures
New RNA and protein NMR methods
Viral pathogens
Bacterial pathogens
Antivirals
Ribosome structure
Translational mechanism and antibiotics
New technologies to study proteins
Solid state NMR
Peptides as drugs
Membrane proteins as drug targets
Structure-based drug design in biotechnology
NMR and physical studies of pathogenic proteins
Coupling genomics and structural studies

Tutorials:

Pathogenesis of bioterror agents
Computational biology and experiment
Technology and the environment
Spectroscopic approaches
Roundtable and tutorial on genome-wide approaches and biophysics
Student-lecturer discussion on future perspectives
Student presentations including a poster session

• Alexander ARSENIEV, Russian Academy of Sciences, RU
• Muriel DELEPIERRE, Institute Pasteur, FR
• Roman EFREMOV, Russian Academy of Sciences, RU
• Angela GRONENBORN, University of Pittsburgh, US
• Michael LEVITT, Stanford University, US
  
• William LIPSCOMB, Harvard University, US
  
• Peter LUKAVSKY, MRC, Laboratory for Molecular Biology, UK
  
• Thomas MARLOVITS, Institute of Molecular Biotechnology GmbH, AT
  
• Alexander McPHERSON, University of California, Irvine, US
  
• Hartmut OSCHKINAT, Berlin Institute of Molecular Pharmacology, GE
  
• Jody PUGLISI, Stanford University, US
  
• Gian Luigi ROSSI, University of Parma, IT
  
• Jamie WILLIAMSON, The Scripps Research Institute, US
  
• Ada YONATH, Weizmann Institute, IL
  

Fee: 1,100 Euro.

Fee includes:

(a) lodging accommodations for the duration of the course at the Ettore Majorana Centre;
(b) all meals (breakfast, lunch, dinner) for the duration of the school;
(c) Banquet Evening;
(d) one excursion day; and,
(e) transportation from the point of entry (Palermo airport or railroad station) as well as return transportation to the same.

Applications Closed. Look for us in two years for Erice 2011.

For additional information please contact:

Ms. Manolia Margaris
E-mail: manolia @at@ stanford.edu (replace " @at@ " with "@")